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Service d'immunologie et allergie
CHUV BH19-610
Rue du Bugnon 46
1011 Lausanne
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RESEARCH PROJECT ON STRUCTURAL FEATURES OF SECRETORY IgA

In this research project, we intended to determine whether free SIgA or SIgA bound to an antigen display the same sensitivity to intestinal proteases and interact with their cognate receptor with the same affinity. Our findings illustrate the concept that structural changes upon antigen binding modify the characteristics of the antibody, and explain specific interaction with M cells in the intestine.

Dr. Blaise Corthésy

Blaise Corthésy, P.D., M.E.R.
Research Director

1997-present:
Head of Research Unit, R&D Laboratory, Division of immunology and Allergy, CHUV, Lausanne; Privat-Docent, University of Lausanne

1993-1997:
Group leader, University of Lausanne and ISREC, Epalinges

1990-1992:
Post-doctoral fellow and Instructor, Stanford University, CA-USA

1986-1989:
Post-doctoral fellow and Maître-assistant, University of Lausanne

1986:
Ph.D. in Biochemistry, University of Geneva

1983:
M.Sc. in Biochemistry, University of Geneva

1982:
B.Sc. in Biochemistry and Chemistry, University of Geneva

Professional Memberships:
Swiss Society for Immuno-Allergy, Society for Mucosal Immunology, French Society for Immunology, Swiss Society for Experimental Biology and Biochemistry

Honor:
2002 Pfizer Research Award in Rheumatology, Immunology and Clinical Immunology

Dernière modification le 30.01.2012 - Impressum - Informations juridiques