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RESEARCH PROJECT IN THE ROLE OF REGULATORY T CELLS
Among the mechanisms of control of the immune response, an active role is played by regulatory T cells that suppress T cell functions. The aim of this research project is to focused on the characterization of naturally occurring CD4+CD25+ regulatory T cells and to identify their precursors. In addition we are investigating the role of regulatory T cells in liver graft rejection.
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Laura Codarri, Ph.D. Post-doctoral Fellow
2001-May 2007: Post-doc on “Identification and characterization of CD4+CD25+Regulatory T cells in cord blood, thymus and peripheral blood” and “Research for allo-specific CD4 and CD8 populations in Liver and Kidney transplanted” Prof. Pantaleo, Division of Immunology and Allergy, CHUV, Lausanne.
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2001: Qualifying examination at Biological Science University of Milan, Italy. 1999-2001: Scientist trainee on “Identification and characterization of receptors for binding and entry of HHV-7 on T cells” Prof. Lusso, Division of Virology, DIBIT, Milan, Italy. 1999: Master’s Degree in Biology, University of Milan (Università degli Studi di Milano). Prof. Lusso, Division of Virology DIBIT, San Raffaele and Prof. Comolli, Division of Immunopathology, Biological Science University of Milan, Italy.
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Selected publications:
- Codarri L., Lieby P., Harari A., Correa R., Garcia M., De Smedt M., Plum J. and Pantaleo G. Identification in the thymus, cord blood and pheripheral blood of the CD4+CD25+CD62L+CD45RO- population as precursors of human naturally occurring CD4+CD25high regulatory T cells . Submitted.
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